Highly efficient one-pot multienzyme (OPME) synthesis of glycans with fluorous-tag assisted purification.
نویسندگان
چکیده
Oligo(ethylene glycol)-linked light fluorous tags have been found to be optimal for conjugating to glycans for both high-yield enzymatic glycosylation reactions using one-pot multienzyme (OPME) systems and quick product purification using fluorous solid-phase extraction (FSPE) cartridges. The combination of OPME glycosylation systems and the FSPE cartridge purification scheme provides a highly effective strategy for facile synthesis and purification of glycans.
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ورودعنوان ژورنال:
- Chemical communications
دوره 50 24 شماره
صفحات -
تاریخ انتشار 2014